What is the Primary Progressive Multiple Sclerosis and Secondary Progressive Multiple Sclerosis?

Primary Progressive Multiple Sclerosis is defined by the MSIF as “a lack of distinct attacks, but with slow onset and steadily worsening symptoms.” Neurologic functions are also expected to worsen with PPMS. Patients with active PPMS should focus on treatments with disease-modifying therapy to reduce potential relapses and increase physical rehabilitation. Patients with stable without activity or progression, MS care providers must also focus on rehabilitation and symptom management. Lastly, inactive PPMS but is progressive must help patients keep safe and independently mobile with rehabilitation strategies.

 

Secondary Progressive Multiple Sclerosis is for patients who have been diagnosed with RRMS but have the development of progressive disability later in the course of the disease. SPMS is characterized by a progressive worsening of neurologic functions. Moreover, SPMS is a second phase of the disease for patients with Multiple Sclerosis. Due to inflammation, patients may or may not continue to experience relapses. The NMSS states that the disease “gradually changes from inflammatory process seen in RRMS to a more steadily progressive phase characterized by nerve damage or loss.” The treatments are also the same with PPMS which includes symptom management, rehabilitation, and healthy living.

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